Does nifedipine affect baby?

Does nifedipine affect baby?

According to the March of Dimes, nifedipine is effective and relatively safe, which is why doctors use it so much. Nifedipine has no side effects for your baby. The possible side effects for you may include: constipation.

Why is nifedipine used in labor and delivery?

Nifedipine is a calcium channel blocker which has been commonly used in the treatment of preterm labor with dilation of the cervix, with good results. However, the main benefit of a tocolytic drug is the prolongation of pregnancy for a 48-hour period to allow the steroid effect to enhance fetal lung maturity.

How long do you take nifedipine for preterm labor?

Nifedipine (N=37): 20 mg orally every 6 h until 37 weeks. It was initiated after discontinuation of acute IV tocolysis. Inclusion: women with singleton or twin pregnancy and intact membranes who had been in active preterm labor successfully arrested with IV magnesium sulfate or oral nifedipine.

Can nifedipine be used in early pregnancy?

Conclusions: The dihydropyridine group of calcium channel blockers (type II calcium blockers) and, specifically, nifedipine are safe for use in pregnancy. They have little teratogenic or fetotoxic potential.

Can I take nifedipine at night?

You can take nifedipine at any time of day, but try to make sure it’s around the same time or times every day. Swallow the capsules or tablets whole with a drink of water.

How long does nifedipine stay in your system?

The elimination half-life of nifedipine is approximately two hours. Only traces (less than 0.1% of the dose) of unchanged form can be detected in the urine. The remainder is excreted in the feces in metabolized form, most likely as a result of biliary excretion.

Why is nifedipine contraindicated in pregnancy?

Conclusion: The results suggest that, in addition to tocolysis, nifedipine can cause vascular dilatation in both the uterus and the placenta. The use of nifedipine within the normal dose range does not appear to adversely affect fetal outcome and may potentially improve fetal outcome in some disorders of pregnancy.

When should a pregnant woman take nifedipine?

What is nifedipine? Nifedipine belong to a group of medications called calcium channel blockers. It is used to treat high blood pressure (hypertension) and chest pain (angina). Sometimes it is used to stop labor before 37 weeks of pregnancy (preterm delivery).

Should nifedipine be taken at night?

Is there an alternative to nifedipine?

Nisoldipine appears to be an effective substitute treatment for nifedipine in severely hypertensive patients sensitive or resistant to nifedipine.