What does a lesion in the corpus callosum mean?

What does a lesion in the corpus callosum mean?

What does a lesion in the corpus callosum mean?

Isolated lesions of the corpus callosum are rare and may represent transient responses to injury or myelination abnormalities. More common butterfly lesions involve the corpus callosum and both cerebral hemispheres—a pattern associated with aggressive tumors, demyelination, and traumatic brain injury.

What does Splenium of corpus callosum mean?

INTRODUCTION. The splenium is the thickest and most posterior portion of the corpus callosum (CC). It consists of numerous axonal fibers that mainly connect both temporal, posterior parietal, and occipital cortices (1). However, until now, the exact function of the splenium of corpus callosum (SCC) is not well known.

What is the function of the Splenium of corpus callosum?

The splenium of the corpus callosum connects the posterior cortices with fibers varying in size from thin late-myelinating axons in the anterior part, predominantly connecting parietal and temporal areas, to thick early-myelinating fibers in the posterior part, linking primary and secondary visual areas.

What does reversible lesion mean?

The reversible lesion in SCC is an MRI finding observable in a wide variety of diseases and conditions. Thus, it should be considered as a secondary change rather than a peculiar feature associated with mild encephalitis/encephalopathy.

Why the corpus callosum is important?

The two hemispheres in your brain are connected by a thick bundle of nerve fibres called the corpus callosum that ensures both sides of the brain can communicate and send signals to each other.

How do you strengthen the corpus callosum?

Experts say using your non-dominant hand helps your brain to better integrate its two hemispheres. Research shows that musicians who use both hands have about a 9 percent increase in the size of their corpus callosum (the part of the brain that connects the two hemispheres).

What is cytotoxic lesion?

Abstract. Cytotoxic lesions of the corpus callosum (CLOCCs) are secondary lesions associated with various entities. CLOCCs have been found in association with drug therapy, malignancy, infection, subarachnoid hemorrhage, metabolic disorders, trauma, and other entities.

What are the etiologies of corpus callosum lesions?

Reported etiologies include 1-5,12 : Transient lesions of the splenium are only really appreciable on MRI where they have three distinct patterns 4,12 : well-circumscribed, small, oval lesions in the midline within the substance of the splenium (most common)

Why is the splenium of the corpus callosum preferentially affected?

It appears that the reason the splenium of the corpus callosum is preferentially affected is the presence of a high density of oligodendrocytes expressing large numbers of glutamate affected receptors 12 .

Which is the thickest part of the corpus callosum?

The splenium is the thickest and most posterior portion of the corpus callosum (CC). It consists of numerous axonal fibers that mainly connect both temporal, posterior parietal, and occipital cortices (1).

Are there any symptoms of corpus callosum disconnection?

Unlike many other lesions of the corpus callosum, CLOCCs do not demonstrate convincing signs or symptoms of hemispheric disconnection, such as pseudo-neglect, alien hand syndrome , apraxia of the left hand, agraphia, alexia, and visual apraxias 4 .