What is acquired keratosis Keratoderma palmaris et plantaris?

What is acquired keratosis Keratoderma palmaris et plantaris?

‘Keratoderma’ is a term that means marked thickening of the epidermis of the skin. ‘Palmoplantar’ refers to the skin on the soles of the feet and palms of the hands; these are the areas keratoderma affects most often. Palmoplantar keratoderma is also sometimes known as ‘keratosis palmaris et plantaris’.

How is keratosis Punctata treated?

Treatment includes keratolytics, topical salicylic acid, mechanical debridement, excision, and topical and systemic retinoids. Punctate keratosis of the palmar creases occurs most commonly in African American patients aged 15-40 years.

What is keratosis Punctata?

Specialty. Dermatology. Keratosis punctata of the palmar creases is a common skin disorder that occurs most often in black patients, with skin lesions that are 1 to 5mm depressions filled with a comedo-like keratinous plug.

What causes keratosis Punctata?

In most families, punctate palmoplantar keratoderma type 1 is caused by a mutation in the AAGAB gene . The gene is thought to play an important role in skin integrity. When the gene is not working properly, the skin clumps together, forming the bumps on the skin that are characteristic of the condition.

What is keratosis palmaris et plantaris?

Keratosis palmaris et plantaris (KPP), also referred to as tylosis and by many other synonyms,* is a heredofamilial ectodermal defect characterized by hyperkeratosis of the palms and soles.

Can acquired keratoderma be cured?

How is palmoplantar keratoderma treated? Inherited palmoplantar keratodermas are not curable but symptoms can be controlled. The aim of treatment is to reduce the thickness of the skin and to soften the skin.

What are palmar pits?

Palmar pits are small depressions in the skin on the palm of the hand that may be seen in individuals with basal cell nevus syndrome, a hereditary syndrome associated with the development of basal cell carcinoma. Depressions may also be seen on the sole of the foot (plantar pits, not shown).

What causes Palmar papules and pits?

Palmar and plantar pits appear as punctiform depressions in the skin of palms and soles of feet. These changes are caused by a partial or complete absence of the stratum corneum. They are usually asymmetric, flesh-, pink- or red-coloured, and range from 2 to 3 mm in diameter and 1 to 3 mm in depth.

Is hyperkeratosis hereditary?

Epidermolytic hyperkeratosis is usually inherited in an autosomal dominant pattern. This means that one copy of a mutated gene is able to cause the disorder and can be inherited from either parent. If one parent is affected, each child has a 50% chance of inheriting the disease.

What is Palmar keratoderma?

Palmoplantar keratoderma (PPK) is a group of skin conditions characterized by thickening of the skin on the palms of the hands and soles of the feet. PPK can also be a feature of various underlying syndromes. In rare forms of PPK, organs other than the skin may also be affected.

What is palmaris et plantaris?

Pustulosis palmaris et plantaris (PPP) is a rare and chronic inflammatory condition that primarily affects the palms of the hands and soles of the feet. Signs and symptoms of the condition generally develop during adulthood and include crops of pustules on one or both hands and/or feet that erupt repeatedly over time.