What is an example of cell adhesion?

What is an example of cell adhesion?

An example of a pathogenic protozoan is the malarial parasite (Plasmodium falciparum), which uses one adhesion molecule called the circumsporozoite protein to bind to liver cells, and another adhesion molecule called the merozoite surface protein to bind red blood cells.

Is Collagen a cell adhesion molecule?

The collagen family members as cell adhesion proteins.

What type of proteins are cadherins?

Cadherins (named for “calcium-dependent adhesion”) are a type of cell adhesion molecule (CAM) that are important in the formation of adherens junctions to bind cells with each other. Cadherins are a class of type-1 transmembrane proteins, and they are dependent on calcium (Ca2+) ions to function, hence their name.

What are the types of adhesion molecules?

Adhesion molecules are generally divided into five groups: integrins (discussed in greater detail below), selectins, cadherins, members of the immunoglobulin superfamily (IgSF) including nectins and others such as mucins (9).

What does cadherin protein do?

Cadherins are transmembrane proteins that mediate cell–cell adhesion in animals. By regulating contact formation and stability, cadherins play a crucial role in tissue morphogenesis and homeostasis.

How do adhesion proteins work?

Cell adhesion molecules (CAMs) are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings.

What are adhesion proteins made of?

Integrin molecules are composed of two chains of amino acids, one of which is connected to the actin filaments in the cytoskeleton, while the other is connected to the SAMs. This enables external activity in the extracellular matrix to affect the shape and movement of the cell.