What is considered a large DCIS?

What is considered a large DCIS?

The mean length of the largest dimension of DCIS was 1.4 cm (range, 0.3–5.4 cm).

What does Comedo necrosis mean?

High-grade DCIS is sometimes described as “comedo” or “comedo necrosis.” Comedo refers to areas of dead (necrotic) cancer cells, which build up inside the tumor. When cancer cells grow quickly, some cells don’t get enough nourishment. These starved cells can die off, leaving areas of necrosis.

What percentage of high grade DCIS becomes invasive?

The largest studies on the natural history of DCIS suggest that more than 50% of patients with high-grade DCIS have the potential to progress to an invasive carcinoma in less than 5 years if left untreated, while low-grade DCIS has a similar progression but in a small percentage of patients (35–50%) and in a more …

Can biopsy cause DCIS to spread?

Won’t a Needle Biopsy Cause Cancer Cells to Spread? Patients are often concerned that the needle biopsy will disrupt and disseminate cancer cells, but this is not the case.

What is the survival rate for high grade DCIS?

In spite of the unknown, the overall prognosis for DCIS is excellent with appropriate surgical and oncologic management (approximately 98% long-term survival). DCIS is typically treated with wide surgical resection with or without radiation therapy; there is an evolving role for hormonal therapy.

How quickly does DCIS spread?

It assumes that all breast carcinomas begin as DCIS and take 9 years to go from a single cell to an invasive lesion for the slowest growing lesions, 6 years for intermediate growing DCIS lesions, and 3 years for fast-growing DCIS lesions.

What is the best treatment for high grade DCIS?

Standard treatment options for DCIS include: Lumpectomy followed by radiation therapy: This is the most common treatment for DCIS. Lumpectomy is sometimes called breast-conserving treatment because most of the breast is saved. Mastectomy: Mastectomy, or removal of the breast, is recommended in some cases.