What is sorbitan solution?

What is sorbitan solution?

» Sorbitol Sorbitan Solution is a water solution containing, on the anhydrous basis, not less than 25.0 percent of D-sorbitol (C6H14O6) and not less than 15.0 percent of 1,4-sorbitan (C6H12O5). A: Prepare a solution containing 1.4 g of Sorbitol Sorbitan Solution in 75 mL of water.

What is a USP monograph?

An Overview of USP Monographs. Monographs articulate the quality expectations for a medicine including for its identity, strength, purity, and performance. They also describe the tests to validate that a medicine and its ingredients meet these criteria.

What is dextrose usp?

Dextrose (hydrous dextrose) Injection, USP is a sterile, nonpyrogenic solution for fluid replenishment and caloric supply in single dose containers for intravenous administration. It contains no antimicrobial agents.

Which is test for analyzing dextrose for IV preparation?

Add phenolphthalein TS. Test preparation: 4.0 g of Dextrose in water to make Analysis: Titrate with 0.020 N sodium hydroxide to 25 mL the production of a distinct pink color. Acceptance criteria: NMT 0.30 mL■2S (USP39) Analysis: To the Sample solution add 25 µL of iodine TS.

What are the bad side effects of sorbitol?

Common side effects of sorbitol include:

• Abdominal discomfort.
• Dehydration.
• Diarrhea.
• Dry mouth.
• Excessive bowel activity.
• Fluid and electrolyte losses.
• High blood sugar (hyperglycemia)
• Lactic acidosis.

How bad is sorbitol?

Consuming sorbitol or other sugar alcohols in large amounts can cause bloating and diarrhea in some people, especially if you’re not used to regularly consuming them. This can be an unwelcome result for some, but the desired effect for those using it to promote bowel activity.

What is dextrose 5% used for?

Dextrose is a form of glucose (sugar). Dextrose 5% in water is injected into a vein through an IV to replace lost fluids and provide carbohydrates to the body. Dextrose 5% in water is used to treat low blood sugar (hypoglycemia), insulin shock, or dehydration (fluid loss).

Is the anhydrous form of dextrose in the USP?

Modified the verbiage in accordance with PDG sign-off document. EP and JP refer to Dextrose as “Glucose” and have split the anhydrous and monohydrate forms into two separate monographs. USP will maintain one Dextrose monograph to incorporate both the anhydrous and monohydrate forms.

How many USP monographs are there for dextrose?

USP will maintain one Dextrose monograph to incorporate both the anhydrous and monohydrate forms. Added Infrared, Chromatographic identity, and Water tests for ID test. Removed the ID test by color reaction. Added the new assay test by liquid chromatography.

How to dissolve sorbitol sorbitan Rs in water?

USP Sorbitol RS and USP 1,4-Sorbitan RS in water to obtain a so-. Limit of nickel— lution having concentrations of about 10mg per g and 4mg per g, Test solution—Dissolve 20.0g of Sorbitol Sorbitan Solution inrespectively.

How much dextrose is in a sterile solution?

» Dextrose Injection is a sterile solution of Dextrose in Water for Injection. It contains not less than 95.0 percent and not more than 105.0 percent of the labeled amount of dextrose (C 6 H 12 O 6 ·H 2 O).