What is the life cycle of Borrelia burgdorferi?

What is the life cycle of Borrelia burgdorferi?

What is the life cycle of Borrelia burgdorferi?

The various species of Borrelia are known to humans in the form of Lyme disease and recurring fever, transmitted through tick or flea bite. The cycle of Borrelia through animals is related to the tick’s life cycle. The tick has four stages in its two-year life cycle, egg, larva, nymph and adult.

How does Borrelia burgdorferi reproduce?

burgdorferi reproduces asexually through mitosis to make a colony. The species has not yet been found naturally outside of a host, and therefore it needs a host in order to reproduce.

How long is the life cycle for the vector of Lyme disease?

Knowing the complex life cycle of the ticks that transmit Lyme disease is important in understanding the risk of acquiring the disease and in finding ways to prevent it. The life cycle of these ticks requires 2 years to complete.

Where does Borrelia burgdorferi live in the body?

Animal studies have shown that Borrelia burgdorferi can be found in many tissues and organs including the skin, joints, heart, brain, bladder and other sites of untreated animals as well as in animals who receive antibiotic treatment (Barthold, 2012, and Embers, Barthold, Borda et. al., 2012).

What does Borrelia burgdorferi do to the body?

Lyme disease is caused by a spirochete—a corkscrew-shaped bacterium called Borrelia burgdorferi. Lyme is called “The Great Imitator,” because its symptoms mimic many other diseases. It can affect any organ of the body, including the brain and nervous system, muscles and joints, and the heart.

What are the symptoms of Borrelia burgdorferi?

Lyme disease is caused by the bacterium Borrelia burgdorferi and rarely, Borrelia mayonii. It is transmitted to humans through the bite of infected blacklegged ticks. Typical symptoms include fever, headache, fatigue, and a characteristic skin rash called erythema migrans.

Does Lyme disease stay in your body for life?

If treated, Lyme disease does not last for years. However, for some people, the after-effects of the disease can linger for months and sometimes even years.

Can you get Lyme disease without a tick bite?

If parts of its mouth are still stuck in your skin, that’s OK. They will come out on their own and can’t transmit Lyme disease without the tick body attached. It’s best to remove a tick as soon as possible (within 24 hours). The longer an infected tick is attached, the more likely it is to transmit Lyme disease.

Can Borrelia burgdorferi be cured?

Lyme disease is caused by infection with the bacterium Borrelia burgdorferi. Although most cases of Lyme disease can be cured with a 2- to 4-week course of oral antibiotics, patients can sometimes have symptoms of pain, fatigue, or difficulty thinking that lasts for more than 6 months after they finish treatment.

How does the infectious cycle of B burgdorferi work?

The infectious cycle of B burgdorferi involves colonization, infection of Ixodes ticks, and then transmission to broad a range of mammalian hosts, including humans. Variation in environmental and host conditions promotes different gene expression and changes in the composition of the membrane proteins of the spirochete.

When does an ixodid tick become infected with burgdorferi?

Ixodid ticks have a 2-year, 3-stage life cycle (Figures 2and ​and3).3). The larvae hatch in the early summer and are not infected with B burgdorferi. The tick may become infected at any stage of its life cycle by feeding on a host that is a natural reservoir for B burgdorferi, such as chipmunks or white-footed mice.

How does B.burgdorferi differ from other spirochetes?

B. burgdorferi resembles other spirochetes in that it has an outer membrane and inner membrane with a thin layer of peptidoglycan in between.

What kind of animal does Borrelia burgdorferi live in?

The spirochete Borrelia burgdorferi is a tick-borne obligate parasite whose normal reservoir is a variety of small mammals [1].