What does Pachydermoperiostosis mean?

What does Pachydermoperiostosis mean?

Pachydermoperiostosis is a rare disorder characterized by clubbing of the fingers, thickening of the skin of the face (pachyderma), and excessive sweating (hyperhidrosis). It typically appears during childhood or adolescence, often around the time of puberty, and progresses slowly for about ten years.

What causes Osteoarthropathy?

Hypertrophic osteoarthropathy (HOA) is mainly caused by mainly fibrovascular proliferation. It is characterized by a combination of clinical findings, including severe disabling arthralgia and arthritis, digital clubbing, and periostosis of tubular bones with or without synovial effusion.

How is hypertrophic osteoarthropathy diagnosed?

The diagnostic criteria for hypertrophic osteoarthropathy (HOA) include clubbing and periostosis of the tubular bones. Three incomplete forms of hypertrophic osteoarthropathy are described: Clubbing alone. Periostosis without clubbing in the setting of an illness known to be associated with HOA.

What is hypertrophic osteoarthropathy?

Hypertrophic osteoarthropathy (HOA) is a medical condition characterized by abnormal proliferation of skin and periosteal tissues involving the extremities and characterized by three clinical features: digital clubbing (also termed Hippocratic fingers), periostosis of tubular bones, and synovial effusions.

Can clubbed fingers be genetic?

Clubbing may be present as an hereditary anomaly in selected families. When this anomaly is observed in a presumably healthy person, inquiry into the duration of the abnormality and the possible familial distribution may be rewarding.

How is hypertrophic osteoarthropathy treated?

Primary hypertrophic osteoarthropathy Medical care is palliative and includes nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, tamoxifen, retinoids, and risedronate to alleviate the painful polyarthritis/osteoarthropathy. Colchicine may be helpful for the pain due to subperiosteal new bone formation.

Is hypertrophic osteoarthropathy painful?

Hypertrophic osteoarthropathy (HOA) is a syndrome most commonly associated with non-small cell lung cancer and consists of periostitis, digital clubbing and painful polyarthropathy. Its symptoms may be disabling and are reportedly difficult to manage effectively with conventional analgesia.

Does hypertrophic osteodystrophy go away?

Especially in large/giant breed puppies, inflammation in the growth plates of longer, larger bones can lead to what’s known as hypertrophic osteodystrophy (HOD). While HOD can be very painful, it is usually a self-limiting condition with no permanent side-effects, meaning puppies simply outgrow it.

Does COPD cause clubbing?

Chronic obstructive pulmonary disease (COPD) per se does not cause clubbing, but if clubbing is present in COPD, underlying lung cancer and bronchiectasis must be ruled out.

When was Pachydermoperiostosis first described as a disorder?

Pachydermoperiostosis or primary hypertropic osteoarthropathy is a rare hereditary disorder that was first described in 1868. It is characterized by digital clubbing, pachydermia (thickening of the facial skin and/or scalp), and periostosis (swelling of periarticular tissue and subperiosteal new bone formation).

How is Pachydermoperiostosis related to osteoarthropathy?

Pachydermoperiostosis or primary hypertropic osteoarthropathy is a rare hereditary disorder that was first described in 1868. It is characterized by digital clubbing, pachydermia (thickening of the facial skin and/or scalp), and periostosis (swelling of periarticular tissue and subperiosteal new bone formation), as shown in the images below. [ 2]

What are the treatment options for Pachydermoperiostosis?

Treatment is aimed at addressing the specific symptoms present in each individual and may include nonsteroidal anti-inflammatory medications for pain and swelling of joints, retinoid treatment of skin symptoms, and plastic surgery for facial involvement. [1] [2] This table lists symptoms that people with this disease may have.

How is Pachydermoperiostosis related to bronchogenic carcinoma?

An AD condition characterized by induration of skin in natural folds, accentuation of creases of face and scalp, finger clubbing and periostosis of long bones; acquired pachydermoperiostosis is linked to bronchogenic carcinoma, termed hypertrophic–pulmonary osteoarthropathy, see there. Want to thank TFD for its existence?