What drugs contain coumarin?

What drugs contain coumarin?

What drugs contain coumarin?

Some naturally occurring coumarin derivatives include warfarin (2), umbelliferone (7-hydroxycoumarin, 3), aesculetin (6,7-dihydroxycoumarin, 4), herniarin (7-methoxycoumarin, 5), psoralen (6) and imperatorin (7).

What is the drug coumarin used for?

Coumarins are commonly used in the treatment of prostate cancer, renal cell carcinoma and leukemia, and they also have the ability to counteract the side effects caused by radiotherapy. Both natural and synthetic coumarin derivatives draw attention due to their photochemotherapy and therapeutic applications in cancer.

What are coumarin anticoagulants?

Coumarin anticoagulants inhibit the release of plasma clotting factor VII by vitamin K in liver slices from vitamin K-deficient animals without inhibition of protein synthesis. When the ratio of vitamin K to coumarin anticoagulant is kept constant, but the concentrations are increased, the inhibition disappears.

Where is coumarin found?

What is coumarin and where is it found? Coumarin is a natural flavouring and fragrant substance contained in many plants. It is contained in relatively high concentrations in varieties of cinnamon collectively known as “Cassia cinnamon” and also, for example, in woodruff, tonka beans and melilot.

Is Coumadin made from coumarin?

Coumarin is used to make coumadin, but coumarin is not anti-coagulant itself.

What foods contain coumarin?

Coumarin, or is 1,2-benzopyrone, occurs naturally in tonka beans and cinnamon, but can also be found in trace amounts in bison grass, green tea, carrots, and even some beers.

What is the other name of coumarin?

Coumarin

Names
Preferred IUPAC name 2H-1-Benzopyran-2-one
Other names 1-Benzopyran-2-one
Identifiers
CAS Number 91-64-5

What foods are high in coumarin?