Can you have both metabolic acidosis and alkalosis?

Can you have both metabolic acidosis and alkalosis?

Can you have both metabolic acidosis and alkalosis?

It is possible for a person to have more than one acid-base disorder at the same time. Examples include ingestion of aspirin (which can produce both a respiratory alkalosis and metabolic acidosis) and those with lung disease who are taking diuretics (respiratory acidosis plus metabolic alkalosis).

What are the causes of mixed acidosis?

It can be caused by:

  • Cancer.
  • Carbon monoxide poisoning.
  • Drinking too much alcohol.
  • Exercising vigorously for a very long time.
  • Liver failure.
  • Low blood sugar (hypoglycemia)
  • Medicines, such as salicylates, metformin, anti-retrovirals.
  • MELAS (a very rare genetic mitochondrial disorder that affects energy production)

What causes mixed respiratory and metabolic alkalosis?

Common causes include prolonged vomiting, hypovolemia, diuretic use, and hypokalemia. Renal impairment of HCO3− excretion must be present to sustain alkalosis. Symptoms and signs in severe cases include headache, lethargy, and tetany.

What is a mixed metabolic acidosis?

Pattern: The combination of a high pCO2 and a low bicarbonate means that a mixed disorder is present: there must be 2 or more primary acid-base disorders present. This pattern is found with a combined acidosis: metabolic acidosis (low bicarbonate) and a respiratory acidosis (high pCO2).

What is the best treatment for metabolic acidosis?

Acidosis treatment might include:

  • oral or intravenous sodium bicarbonate to raise blood pH.
  • medications to dilate your airways.
  • continuous positive airway pressure (CPAP) device to facilitate breathing.
  • sodium citrate to treat kidney failure.
  • insulin and intravenous fluids to treat ketoacidosis.

How does the body respond to metabolic alkalosis?

Your body compensates for both alkalosis and acidosis mainly through your lungs. The lungs change the alkalinity of your blood by allowing more or less carbon dioxide to escape as you breathe. The kidneys also play a role by controlling the elimination of bicarbonate ions.

What is the treatment of metabolic alkalosis?

Metabolic alkalosis is treated by replacing water and mineral salts such as sodium and potassium (electrolytes) and correcting the cause. Respiratory alkalosis is treated by correcting the cause.

What are GI signs and symptoms of metabolic acidosis?


  • Gastroesophagael reflux
  • Skin eruptions
  • Sunken eyes
  • Gastritis
  • Ulcers
  • Poor digestion
  • Dark circles under the eyes
  • Foul-smelling stools
  • Anal itching
  • What is the prognosis of metabolic acidosis?

    Acute Metabolic Acidosis most often occurs during hospitalizations, and acute critical illnesses. It is often associated with poor prognosis, with a mortality rate as high as 57% if the pH remains untreated at 7.20. At lower pH levels, acute metabolic acidosis can lead to impaired circulation and end organ function.

    What are factors cause alkalosis?

    Hypokalemic alkalosis. Hypokalemic alkalosis occurs when your body lacks the normal amount of the mineral potassium. You normally get potassium from your food, but not eating enough of it is rarely the cause of a potassium deficiency. Kidney disease, excessive sweating, and diarrhea are just a few ways you can lose too much potassium.

    Why does severe vomiting would result to metabolic acidosis?

    Metabolic alkalosis most commonly results from severe cases of vomiting that cause you to lose the acidic fluids in your stomach. This can usually be reversed by treatment with a saline solution. It can also be the result of a potassium deficiency or a chloride deficiency .